Scientific Article

Stage of fibrosis is not a predictive determinant of weight loss in patients undergoing bariatric surgery

Obesity and nonalcoholic fatty liver disease (NAFLD) are an increasing health care burden worldwide. Weight loss is currently the best option to alleviate NAFLD and is efficiently achieved by bariatric surgery. Presence of NAFLD seems to be predictive for postoperative weight loss. To date, only few predictive factors for postbariatric weight loss (age, diabetes, psychiatric disorders) are established.

Since liver fibrosis is the pathogenic driver for the progression of liver disease, we investigated its role in predicting postoperative weight loss. This study focuses on the correlation between fibrosis stage and weight loss.

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Brol, M.J., Drebber, U., Yu, X., Schierwagen, R., Gu, W., Plamper, A., Klein, S., Odenthal, M., Uschner, F.E., Praktiknjo, M., Trebicka, J., Rheinwalt, K.P. Stage of fibrosis is not a predictive determinant of weight loss in patients undergoing bariatric surgery. Surg Obes Relat Dis. 2024 Feb 24
(24)00078-9. doi: 10.1016/j.soard.2024.02.006. Epub ahead of print. PMID: 38522962.

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